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usually relatively uniformly hyperintense.findings are especially important if diffusion-weighted imaging is inadequate.findings are usually non-specific on T2 weighted images.
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#Prostate mr contrast volume manual
measured by automated, semi-automated or manual segmentation methods.Important measurements include the following: Prostate Imaging-Reporting and Data System (PI-RADS).Scoring system used in the assessment of an MRI of the prostate are: Prostate anatomy is not that complex, however, a systematic review is still essential since the clinical relevant pathology being prostate cancer has different mimickers and can be easily confused with other benign findings, artefacts or anatomical structures. Standardized imaging acquisition is important.Ī multiparametric MRI (mpMRI) of the prostate usually consists of the following sequences:Ī biparametric MRI of the prostate features the following sequences: tumor volume within the biopsy sample >50%.maximum number of positive biopsy samples >2.signs of extraprostatic extension (on biopsy or imaging).tumor volume >0.5 mL (translates to a focus of ≥8 x 8 x 8 mm).prostate specific antigen >10 ng/mL or PSA density >0.15 ng/mL.Risk-stratification of prostate cancer has been based on clinical grounds and clinically significant prostate cancer has been defined as one of the following (biopsy results will not be available in primary detection cases) 1-4: Unfortunately, the available clinical information will be most often confined to a recent PSA and the details the patient can give you. previous prostate infections or a history of prostatitis.medications: androgen deprivation therapy (ADT), alpha-blockers etc.location and Gleason score of positive biopsies (% core involvement).free/total PSA ratio (if PSA is between 4-10 ng/mL, no use if PSA >10 ng/mL ).PSA density (can be calculated if a recent PSA level is available).age and ethnicity (men of African descent carry a higher risk).Important clinical information includes the following 1-4: Clinical information is important and can be paramount in the assessment of more subtle findings and the differentiation of an equivocal finding versus findings of low or high probability.